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Our immune system is an evolutionary masterpiece. Every day it protects us from the thousands of different viruses, bacteria and other microbes that attempt to invade our bodies. Without a functioning immune system, we would not survive. One of the immune system’s marvels is its ability to identify pathogens and differentiate them from the body’s own cells. The microbes that threaten our health do not wear a uniform – they all have different appearances. Many have also developed similarities to human cells, as a form of camouflage. So how does the immune system keep track of what to attack and what to protect? Why doesn’t the immune system attack our bodies more frequently? Researchers long believed they knew the answer to these questions: that immune cells mature through a process called central immune tolerance (see image). However, our immune system turned out to be more complex than they believed. Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi have been awarded the 2025 Nobel Prize in Physiology or Medicine for their discoveries concerning peripheral immune tolerance.

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🔆 People’s Plan Campaign (PPC) 2025–26: Viksit Panchayats for Viksit Bharat 📍 Background ✅ The People’s Plan Campaign (PPC) was launched in 2018 under the theme “Sabki Yojana, Sabka Vikas” to prepare participatory Panchayat Development Plans (PDPs) annually. ✅ Institutionalized under the 73rd Constitutional Amendment Act, 1992, Panchayats are empowered under Article 243G to prepare and implement plans for economic development and social justice. 📍 About PPC 2025–26 ✅ Launched on 2nd October 2025 across all States and UTs by the Ministry of Panchayati Raj to prepare PDPs for FY 2026–27. ✅ Focus: Strengthening grassroots governance, enhancing transparency, and ensuring inclusive, participatory planning. ✅ Covers all 29 subjects of the Eleventh Schedule of the Constitution aligned with Sustainable Development Goals (SDGs). 📍 Implementation Framework ✅ Gram Panchayat Development Plans (GPDPs), Block Panchayat Development Plans (BPDPs), and District Panchayat Development Plans (DPDPs) form the three tiers of planning. ✅ Each Gram Sabha uses digital tools like eGramSwaraj, Meri Panchayat App, and Panchayat NIRNAY for plan review and monitoring. ✅ Supported by 20 Line Ministries and 36 converging schemes for effective resource utilization. ✅ Guided by the Panchayat Advancement Index (PAI) and SabhaSaar tool to improve deliberations. 📍 Community Participation ✅ Involves elected representatives, Self-Help Groups (SHGs), Women Elected Representatives (WERs), CBOs, and frontline workers. ✅ Encourages gender-responsive governance and the integration of Village Prosperity and Resilience Plans (VPRPs). ✅ Special focus on tribal empowerment under the Adi Karmayogi Abhiyaan. 📍 Achievements (2019–2025) 📊 Over 18.13 lakh Panchayat Development Plans uploaded (as of 29 July 2025): • 17.73 lakh GPDPs • 35,755 BPDPs • 3,469 DPDPs ✅ Strengthened evidence-based, inclusive, and convergent local planning across rural India. 📍 Significance ✅ Promotes localization of SDGs through a whole-of-government and whole-of-society approach. ✅ Enhances transparency, accountability, and citizen participation in governance. ✅ Contributes to building self-reliant Panchayats, aligning with the vision of Viksit Bharat. #PanchayatiRaj #GrassrootsGovernance

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🔆 Unprecedented Response to India’s Electronics Component Manufacturing Scheme 📍 Overview ✅ The Electronics Component Manufacturing Scheme (ECMS) has received Rs. 1,15,351 crore worth of investments. ✅ The scheme targets creating 1,42,000 direct jobs and a large number of indirect jobs, bolstering India’s self-reliant electronics manufacturing vision. 📍 Key Highlights ✅ 249 applications received, doubling the targeted Rs. 59,350 crore investment. ✅ The estimated production under the scheme is Rs. 10,34,700 crore, with Rs. 4,56,000 crore worth of production expected. 📍 Minister’s Remarks ✅ Ashwini Vaishnaw, Union Minister, urged states to develop a favorable framework to capitalize on this opportunity, creating youth employment and strengthening India’s global manufacturing position. ✅ Shri S. Krishnan highlighted deepening the value chain of electronics manufacturing in India. 🔆 Towards a Self-Reliant India India is emerging as a global hub for electronics manufacturing, expanding domestic value chains and aligning with PM’s vision of self-reliance by 2030-31.

UPSC Prelims Question: Which of the following is/are correct regarding the Electronics Component Manufacturing Scheme (ECMS)? A) The scheme has received investments worth Rs. 1,15,351 crore. B) The scheme targets the creation of 1,42,000 direct jobs. C) The scheme will generate an estimated Rs. 4,56,000 crore worth of production. D) The scheme has 249 applications with a targeted investment of Rs. 59,350 crore. Select the correct answer using the code below: A) 1 and 2 only B) 2 and 3 only C) 1, 2, and 3 only D) 1, 2, 3, and 4 Answer: C) 1, 2, and 3 only



UPSC Mains Question: Analyze the impact of the Electronics Component Manufacturing Scheme (ECMS) on India’s electronics manufacturing ecosystem. How does it contribute to self-reliance and the global competitiveness of India’s electronics sector?

#electronics #manufacturing #economy #selfreliance #governance #prelims #mains

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🔆 Adi Karmayogi Abhiyan: A National Mission for Responsive Governance 📍 Overview ✅ Launched by PM Modi from Dhar, Madhya Pradesh, Adi Karmayogi Abhiyan is a National Mission focused on tribal governance reform. ✅ Ministry of Tribal Affairs is the nodal ministry. ✅ The mission aims to train 20 lakh change-makers for effective governance in over 1 lakh tribal-dominated villages across 30 States. 📍 Key Features ✅ Three Pillars of Leadership: • Adi Karmayogi (Government Officers): Ensure convergence and responsive service delivery at all levels. • Adi Sahyogi (Youth, Teachers, Doctors): Empower youth and community workers in education, health, and innovation. • Adi Saathi (SHG Members, Tribal Elders): Mobilize local communities and preserve traditions. ✅ The mission is tiered, with State Master Trainers (SMTs) leading Regional Process Labs (RPLs) and District Master Trainers (DMTs) for field training. ✅ Convergence with flagship schemes like PM-JANMAN and National Sickle Cell Elimination Mission. 🔆 Impact ✅ 20 lakh trained leaders will ensure effective governance and community-driven development.

UPSC Prelims Question: Which of the following statements about the Adi Karmayogi Abhiyan is/are correct? A) The mission aims to train 20 lakh leaders for effective governance in 1 lakh tribal villages across 30 States. B) Adi Karmayogi focuses on training youth and teachers for governance and service delivery. C) State Master Trainers (SMTs) lead Regional Process Labs and train District Master Trainers (DMTs). D) The initiative primarily targets government officers and SHG members for effective governance. Select the correct answer using the code below: A) 1 and 2 only B) 1, 2 and 3 only C) 1, 3 and 4 only D) 1, 2, 3 and 4 Answer: D) 1, 2, 3 and 4

UPSC Mains Question: Critically assess the Adi Karmayogi Abhiyan in the context of tribal governance. How does the initiative contribute to building participatory, responsive leadership in tribal regions?

#tribal_affairs #society #economy #mains #prelims https://t.me/PIB_UPSC

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🔆 Empowering Farmers through Skill Development & Training 📍 Why in Focus? ✅ Govt has scaled up farmer skilling via KVKs, ATMA, STRY, SMAM, PMKVY, MIDH, RGM, PMKSY, aiming at productivity, resilience & rural incomes . 📍 Key Highlights: ✅ KVKs: Trained 58 lakh farmers (2021–24) through demos & vocational courses . ✅ ATMA: Reached 1.27 cr farmers (2021–25) via trainings, exposure visits, Kisan Melas . ✅ STRY: Skilled 43,000+ rural youth in agri-allied vocations . ✅ SMAM: Mechanisation training for 57,000+ farmers (2021–25) . ✅ Soil Health Card Scheme: 93,000+ trainings & 6.8 lakh demos on balanced fertiliser use . ✅ PMKVY 4.0: Integrated agriculture, trained 1.64 cr (till June 2025). ✅ MIDH: 9.73 lakh horticulture farmers trained (2014–24). ✅ RGM: 38,736 MAITRIs trained for AI services. ✅ PMKSY: 1,601 projects approved; benefitted 34 lakh farmers. 📍 Impact: ✅ Strengthens resilience, market linkages, entrepreneurship. ✅ Builds self-reliant farming community for Viksit Bharat @2047. ✅ Mains Question: Critically analyse India’s approach to farmer skilling and capacity building. How can training initiatives be better aligned with climate adaptation and market competitiveness? ✨ #FarmerEmpowerment #SkillIndia